Bioactive coatings on
metallic implants facilitate joining between the prosthesis and the osseous
tissue, and increase the long-term stability and integrity of the implant.
These are thin films coated on medical devices to deter bacterial adhesion,
improve core functionality of the device, and impart bioactivity along with
biocompatibility to the device. One of the earliest successful bioactive
coatings was that of heparin-modified surface of a polymer blood oxygenator
component trademarked as Caemeda Affinity Blood Oxygenator, Trillium Affinity
NT Blood Oxygenator, which received FDA approval.
Increasing number of
bioactive coating medical devices used for surgeries and medical device
implants are the major driver for the bioactive materials for coating.
Implantable devices
containing thin films of bioactive molecules are rapidly gaining adoption in
therapeutic areas of cardiology and orthopedic joint diseases – the two major
sources of loss of quality of life and disability currently. Bioactive
molecules and generic factors such as increasing incidence of systemic joint
diseases, cardiovascular implant and support are driving the demand for
bioactive coating devices across the globe. On the other hand, lack of research
awareness, high requirement for funding for continued research, and
less-developed research infrastructure in middle and low income countries among
others are the restraints of market.
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The global market for bioactive coating devices is segmented on the basis
of product type, by medical application, by material, and by end-user.
On the basis of
product type, the global market is classified into
Anti-microbial coatings- also termed as self-fertilizing coatings.
Antimicrobial coatings on textiles prevent the degradation of textile fibers, limit
the incidence of bacteria, reduce the formation of odor following the microbial
degradation of perspiration, and protect users by avoiding the transfer and
spread of pathogens.
Hydrophilic coatings- This coating can be applied to many
instruments such as catheters, canulas, and guidewires to prevent or at the
very least reduce the amount of damage and inflammation they cause when being
used on a patient.
Drug Eluting coating- They are statistically superior to
bare-metal stents for the treatment of native coronary artery narrowings., and
others (including Anti-thrombogenic coatings). Antimicrobial coatings are
expected to grow gradually during the forecast period from 2014 to 2025 with
maximum market share.
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